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. 2022 Mar 15;13:830234. doi: 10.3389/fpsyt.2022.830234

Figure 6.

Figure 6

Children do not show a significant difference in sympathetic response to stimuli. Expression of skin conductance as a measure of activity in the sympathetic nervous system. From Vernetti et al. (92). Note the wide range of values in both the control and ASD groups. Eliciting anger, frustration or joy evoked a similar increase in sympathetic activity in the ASD and control group. In response to a fear-inducing stimulus, the control group exhibited an increase while the ASD group exhibited a decrease in sympathetic activity. However, the scatter plots show that most children with ASD and controls have a response that centers around 0, and most values in the ASD group fall within the range of control values. Hence a correct conclusion is that some children with ASD have a decreased arousal response to fear stimuli. The authors did not find a statistically significant difference in baseline sympathetic values and no correlation between the degree of sympathetic responses and the severity of autism. They conclude that toddlers with ASD should not be labeled as “dysregulated” or “upregulated” with respect to autonomic functioning.