Fig. 6.

Schedule and comparative studies of therapeutic efficacy in bleomycin-induced SSc model mice. (A) Schedule of the establishment and treatment of the SSc mouse model. (B) Body weight of Control, PBS, hydrogel, MSCs, and Hy-MSCs groups at different time-points during the induction and treatment of bleomycin-induced SSc model mice. (C) Skin thickness from Control, PBS, hydrogel, MSCs, and Hy-MSCs groups mice after MSCs treatment. (D) Representative images of histopathological changes of Control, PBS, hydrogel, MSCs, and Hy-MSCs groups. The scale bar is 200 μm *P < 0.05, **P < 0.01.