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. 2022 Feb 1;14:364–376. doi: 10.1016/j.bioactmat.2022.01.042

Fig. 4.

Fig. 4

Osteogenic differentiation of op-BMSCs in the conditioned medium: (a) Experimental design of the conditioned culture and analysis; (b–c) ALP activity of op-BMSCs cultured in the RAW264.7 (+) or RAW264.7 (−) conditioned medium of different groups for (b) 3 and (c) 7 days (n = 3 per group); (d) Quantitative results and corresponding images of ECM mineralization of op-BMSCs cultured in the RAW264.7 (+) or RAW264.7 (−) conditioned medium of different groups for 7 days (n = 3 per group). $p < 0.05 by comparing RAW 264.7 (+) to RAW264.7 (−) in each group, *p < 0.05 compared to RAW264.7 (+) in PEEK, #p < 0.05 compared to RAW264.7 (+) in PEEK-ALN, &p < 0.05 compared to RAW264.7 (+) in PEEK-PIII.