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. 2022 Feb 1;14:389–401. doi: 10.1016/j.bioactmat.2022.01.043

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — The macroscopic and microscopic structure of patch matrix. (A) Schematic diagram of cross-linking structure of patch matrix. Green: Sodium alginate. Red: polyacrylamide. (B) Images of the patch matrix before (left) and after (right) coagulation. (C) Photographs of the patch matrix standing and stretching. 1: Patch matrix just removed from the mold. 2: Patch matrix soaked in water for 24 h 3. Patch matrix soaked in 0.25 M calcium chloride for 24 h. a: Stand. b: Stretched. (D) SEM photos of patch matrix soaked in different concentrations of calcium chloride No soaked: Patch matrix just removed from the mold. 0/0.25/0.50/0.75/1.00 M: Patch matrix soaked in 0/0.25/0.50/0.75/1.00 M calcium chloride for 24 h. a: cross section. b: surface.