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. 2022 Jan 21;17:379–393. doi: 10.1016/j.bioactmat.2022.01.007

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 8 — In vivo sequential fluorescence labeling of new bone formation inside porous nwHA bioceramics (yellow, tetracycline label; green, calcein label). (A) Observed patterns of new bone formation. (B) Two types of osteogenesis discovered inside the pore structure of nwHA bioceramics. (C) Comparison of mineral apposition rate (MAR) between different nwHA groups; Statistical analysis of the relationship between osteogenesis type and pore diameter of the bioceramics, and the relationship between osteogenesis type and the MAR.