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. 2022 Mar 15;13:867131. doi: 10.3389/fphar.2022.867131

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LQTS drug studies do not show enhanced integration of diurnal information. (A) Method of ECG recording for LQTS clinical trials that did and not administer a drug. Trials were scored for whether outcomes reported ECG measurements determined by point ECG measurement (black), continual using Holter monitor (dark grey) or outcomes that used both point and continuous measurements (light grey). (B) Distribution of LQTS trials that administered a drug that accounted (orange) or did not account (blue) for time of day information in drug delivery.