Table 2.
Biochemical Parameters of the Subjects
| Variables | KPT2D (n=410) | NKPT2D (n=662) | P value |
|---|---|---|---|
| RBG (mmol/l) | 23.4±9.9 | 17.2±9.3 | <0.001 |
| HbA1c (%) | 12.7±2.3 | 11±2.3 | <0.001 |
| Cr (μmol/l) | 59±13 | 65±26 | <0.001 |
| eGFR (mL/min/1.73m2) | 121.1±16.0 | 106.9±18.9 | <0.001 |
| FPG (mmol/l) | 8.9±2.5 | 7.6±2.0 | <0.001 |
| FCP (pmol/l) | 660.5±257.4 | 771.6±326.7 | <0.001 |
| 2h-PPG (mmol/l) | 20.7±4.8 | 18.2±4.2 | <0.001 |
| 2h-C-P (pmol/l) | 1506.3±634.0 | 2269.0±1083.3 | <0.001 |
| *SBP (mmHg) | 122 (112, 131) | 125 (115, 135) | 0.001 |
| DBP (mmHg) | 75±10 | 77±11 | 0.033 |
| *TG (mmol/l) | 1.73 (1.12, 2.71) | 1.61 (1.15, 2.44) | 0.206 |
| TC (mmol/l) | 5.23±2.21 | 5.15±1.52 | 0.520 |
| LDL-C (mmol/l) | 2.95±0.99 | 3.02±1.00 | 0.269 |
| HDL-C (mmol/l) | 0.89±0.27 | 0.99±0.31 | <0.001 |
| UA (μmol/l) | 318±115 | 316±94 | 0.853 |
| *AST (U/L) | 25 (18, 39) | 25 (19, 38) | 0.672 |
| *ALT (U/L) | 28 (18, 47) | 29 (19, 49) | 0.346 |
| Albumin | 37.4±4.8 | 39.2±4.2 | <0.001 |
| *HOMA-β | 33.02 (22.12, 51.87) | 49.20 (35.32, 78.47) | <0.001 |
| HOMA-IR | 3.48±1.05 | 3.58±1.06 | 0.178 |
| Hypertension | 42.4% | 57.3% | <0.001 |
Notes: Continuous variables are presented as the mean values ±SD or the median values with interquartile ranges (25th to 27th). Categorical variables are presented as percentages. *Non-normal distribution of continuous variables.
Abbreviations: RBG, random blood glucose; HbA1c, glycosylated hemoglobin A1C; Cr, creatinine; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; FCP, fasting C-peptide; 2h-PPG, 2-h post prandial plasma glucose; 2h-C-P, 2-h post prandial C-peptide; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglycerides; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; UA, uric acid; AST, aspartate aminotransferase; ALT, alanine aminotransferase.