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. 2022 Feb 28;13(5):1540–1552. doi: 10.7150/jca.60124

Figure 4.

Figure 4

miR-421 was sponged by circ_0000567. A circ_0000567 was predicted as a miR-421 sponge by CircInteractome, circBank, and starBase. B The predicted binding site between miR-421 and circ_0000567. C Schematic of circ_0000567 wild-type (WT) and mutant luciferase reporter vectors. D Luciferase activity of WT and mutant circ_0000567 after co-transfection with miR-421 mimics. E Expression change of circ_0000567 did not affect miR-421 expression in LUAD cells. F Expression change of miR-421 did not affect circ_0000567 expression in LUAD cells. G miR-421 expression was negatively correlated with circ_0000567 expression.