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. 2022 Feb 21;13(5):1398–1409. doi: 10.7150/jca.58053

Figure 4.

Figure 4

miR-184-5p modulates NUS1 expression by directly targeting NUS1-3'-UTR. (A) There is a putative binding site of miR-184-5p in the 3'-UTR of NUS1. (B) Activity transfected with miR-184-5p mimic and psiCHECK-WT significantly decreased, while no significant difference was observed in the cotransfection reporter activity with miR-184-5p mimic psiCHECK-Mutant. (C-D) Transcriptional and protein expression levels alteration of NUS1 was validated after transfecting miR-184-5p mimic or inhibitor into A-498 and 786-O cells. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.