TABLE 1.

Modified Duke criteria

Major criteria	Minor criteria
Echocardiogram consistent with IE	Rectal temperature ≥39°C
Vegetative lesions	New or worsening heart murmur
Erosive lesion	Predisposing cardiac disease (subaortic stenosis)
Abscess	Evidence of thromboembolic disease
Greater than trivial valvular insufficiency	Evidence of secondary immune‐mediated disease
	Microbiologic findings not meeting major criteria
Positive blood cultures with	Positive Bartonella serology
≥2 bottles with typical organism	Blood cultures not meeting major criteria
≥3 bottles with common skin contaminant
Persistent positive cultures over ≥12 hours