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Tissue specific influence of SVA_67 genotype. Using the PPMI cohort, isoforms ARL17A-203 (A) and CRHR1-203 (C) show significantly reduced expression with PP genotype, while the opposite effect is observed when using the NYGC ALS cohort (B,D). Wilcoxon test was applied to demonstrate statistical significance indicated as asterisks. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001, ns > 0.05.
