TABLE 1.

Analysed gene isoforms in this study and their specifics.

Name	Transcript ID	bp	Protein	Biotype	Location on chromosome 17	Distance SVA_67 to TSS (bp)
MAPT-201	ENST00000262410	6,815	833aa	PC	45,894,554–46,028,334	342,965
MAPT-202	ENST00000334239	1,107	352aa	PC	45,894,668–46,024,183	342,851
MAPT-203	ENST00000344290	2,609	736aa	PC	45,894,560–46,024,425	342,959
MAPT-204	ENST00000351559	5,639	441aa	PC	45,894,554–46,028,334	342,965
MAPT-205	ENST00000415613	2,331	776aa	PC	45,962,338–46,024,171	275,181
MAPT-206	ENST00000420682	1,239	412aa	PC	45,962,338–46,024,171	275,181
MAPT-207	ENST00000431008	1,233	410aa	PC	45,962,338–46,024,171	275,181
MAPT-208	ENST00000446361	5,345	383aa	PC	45,894,674–46,028,334	342,845
MAPT-209	ENST00000535772	1,353	381aa	PC	45,894,551–46,024,225	342,968
MAPT-210	ENST00000570299	889	-	PT	45,894,576–46,018,730	342,943
MAPT-211	ENST00000571311	544	59aa	NMD	45,894,566–45,978,425	342,953
MAPT-212	ENST00000571987	2,277	758aa	PC	45,962,338–46,024,171	275,181
MAPT-213	ENST00000572440	5,015	-	RI	45,975,492–45,980,506	262,027
MAPT-215	ENST00000576518	6,778	-	RI	45,972,783–46,024,431	264,736
MAPT-217	ENST00000680542	2,988	412aa	PC	45,894,663–46,025,873	342,856
MAPT-218	ENST00000680674	1,936	424aa	PC	45,894,527–46,024,655	342,992
KANSL1-201	ENST00000262419	5,309	1105aa	PC	46,029,956–46,192,800	44,719
KANSL1-202	ENST00000432791	5,574	1105aa	PC	46,029,916–46,193,429	44,090
KANSL1-203	ENST00000571698	2,276	678aa	PC	46,039,870–46,193,901	43,618
KANSL1-204	ENST00000572218	9,095	-	RI	46,029,916–46,046,121	191,398
KANSL1-205	ENST00000572904	4,973	1105aa	PC	46,029,916–46,223,676	13,843
KANSL1-206	ENST00000573286	5,437	-	RI	46,037,325–46,043,101	194,418
KANSL1-207	ENST00000573682	358	-	RI	46,032,165–46,033,512	204,007
KANSL1-208	ENST00000574590	5,147	1104aa	PC	46,029,916–46,225,389	12,130
KANSL1-209	ENST00000574655	1,681	-	PT	46,152,904–46,225,371	12,148
KANSL1-210	ENST00000574963	1,493	-	RI	46,031,074–46,032,566	204,953
KANSL1-211	ENST00000575318	4,935	1041aa	PC	46,029,917–46,225,367	12,152
KANSL1-212	ENST00000576137	815	-	RI	46,033,099–46,039,075	198,444
KANSL1-213	ENST00000576248	452	-	PT	46,119,967–46,171,223	66,296
KANSL1-214	ENST00000576739	592	9aa	PC	46,172,117–46,224,902	12,617
KANSL1-215	ENST00000576870	2,848	-	RI	46,029,918–46,040,065	197,454
KANSL1-216	ENST00000577114	629	-	PT	46,050,650–46,121,338	116,181
KANSL1-217	ENST00000638269	3,365	-	RI	46,092,870–46,225,361	12,158
KANSL1-218	ENST00000638275	5,352	1041aa	PC	46,029,917–46,193,400	44,119
KANSL1-220	ENST00000638551	899	-	PT	46,032,186–46,035,160	202,359
KANSL1-221	ENST00000638902	1,971	-	RI	46,170,277–46,223,685	13,834
KANSL1-222	ENST00000639099	1,724	-	PT	46,152,904–46,225,367	12,152
KANSL1-223	ENST00000639150	1,815	523aa	PC	46,033,080–46,224,693	12,826
KANSL1-224	ENST00000639279	387	-	PT	46,088,428–46,094,641	142,878
KANSL1-225	ENST00000639356	1,717	-	PT	46,148,125–46,225,367	12,152
KANSL1-226	ENST00000639375	3,392	-	RI	46,049,399–46,225,355	12,164
KANSL1-228	ENST00000639520	2,655	-	PT	46,221,186–46,225,376	12,143
KANSL1-229	ENST00000639531	2,731	897aa	PC	46,032,257–46,172,183	65,336
KANSL1-231	ENST00000639853	1,425	475aa	PC	46,038,636–46,171,416	66,103
KANSL1-233	ENST00000640519	1,970	-	PT	46,033,045–46,035,924	201,595
KANSL1-236	ENST00000648792	4,933	1061aa	PC	46,029,985–46,225,373	12,146
PLEKHM1-201	ENST00000430334	5,240	1056aa	PC	45,435,900–45,490,721	746,798
PLEKHM1-202	ENST00000446609	2,825	63aa	NMD	45,440,163–45,487,858	749,661
PLEKHM1-203	ENST00000579131	499	-	PT	45,437,916–45,441,059	796,460
PLEKHM1-204	ENST00000579197	4,995	63aa	NMD	45,435,904–45,490,728	746,791
PLEKHM1-205	ENST00000580205	2,385	-	PT	45,452,938–45,460,432	777,087
PLEKHM1-206	ENST00000580404	2,628	-	PT	45,435,903–45,446,273	791,246
PLEKHM1-207	ENST00000581448	3,292	335aa	NMD	45,437,471–45,490,729	746,790
PLEKHM1-208	ENST00000581932	1,163	-	RI	45,477,074–45,482,525	754,994
PLEKHM1-209	ENST00000582035	1,834	-	RI	45,452,938–45,454,771	782,748
PLEKHM1-211	ENST00000583150	479	-	PT	45,439,615–45,448,112	789,407
PLEKHM1-212	ENST00000584420	603	140aa	PC	45,475,211–45,490,738	746,781
PLEKHM1-213	ENST00000585506	332	-	RI	45,439,514–45,440,373	797,146
PLEKHM1-214	ENST00000586084	553	99aa	NMD	45,475,696–45,490,741	746,778
PLEKHM1-215	ENST00000586562	550	-	PT	45,475,597–45,490,749	746,770
PLEKHM1-216	ENST00000589780	587	152aa	PC	45,475,366–45,490,741	746,778
PLEKHM1-217	ENST00000590991	327	45aa	NMD	45,439,546–45,445,507	792,012
PLEKHM1-218	ENST00000591580	650	113aa	PC	45,437,549–45,445,533	791,986
CRHR1-201	ENST00000293493	2,621	430aa	PC	45,784,280–45,835,827	453,239
CRHR1-202	ENST00000314537	2,537	415aa	PC	45,784,320–45,835,828	453,199
CRHR1-203	ENST00000339069	2,490	314aa	PC	45,784,280–45,835,827	453,239
CRHR1-204	ENST00000347197	2,462	145aa	NMD	45,784,307–45,835,825	453,212
CRHR1-205	ENST00000352855	1,146	375aa	PC	45,784,527–45,834,764	452,992
CRHR1-206	ENST00000398285	2,399	444aa	PC	45,784,545–45,835,828	452,974
CRHR1-207	ENST00000535778	1,272	52aa	NMD	45,833,138–45,835,644	404,381
CRHR1-208	ENST00000577353	1,206	401aa	PC	45,784,545–45,834,764	452,974
CRHR1-209	ENST00000580876	223	75aa	PC	45,833,138–45,834,645	404,381
CRHR1-210	ENST00000580955	479	93aa	NMD	45,807,074–45,830,125	430,445
CRHR1-211	ENST00000581479	606	-	RI	45,830,400–45,833,202	407,119
CRHR1-212	ENST00000582766	828	-	RI	45,784,569–45,830,940	452,950
CRHR1-213	ENST00000583888	777	152aa	NMD	45,816,558–45,834,841	420,961
CRHR1-214	ENST00000619154	2,370	154aa	PC	45,784,280–45,835,827	453,239
ARL17A-202	ENST00000336125	5,242	177aa	PC	46,552,756–46,579,691	341,465
ARL17A-203	ENST00000445552	798	125aa	PC	46,516,702–46,579,670	342,151
ARL17A-206	ENST00000622488	524	88aa	PC	46,528,685–46,579,673	342,154
LRRC37A-201	ENST00000320254	5,177	1700aa	PC	46,295,131–46,337,794	56,905
LRRC37A-202	ENST00000393465	4,997	1635aa	PC	46,295,099–46,337,777	57,580
LRRC37A-203	ENST00000496930	3,860	738aa	PC	46,292,733–46,337,792	55,214

PC, protein coding; PT, processed transcript; NMD, non-sense mediated decay; RI, retained intron; TSS, transcriptional start site.