Table 3.
Bacteria/Fungi/Protozoa in TME and their potential functions and therapeutics
| Bacteria/Fungi/Protozoa | Tumor | Function | Therapeutic approach | Ref | |
|---|---|---|---|---|---|
| Bacteria | Anaerococcus mediterraneensis | Colorectal cancer | Unknown | 96 | |
| Bacillus cereus | Colorectal cancer | Unknown | 96 | ||
| Bacteroides fragilis | Colorectal cancer | Unknown | 96 | ||
| Enterococcus faecalis | Colorectal cancer | Unknown | 96 | ||
| Escherichia coli | Colorectal cancer and liver metastasis | Unknown | 96 | ||
| Fusobacterium hwasookii | Colorectal cancer | Unknown | 96 | ||
| Fusobacterium nucleatum | Colorectal cancer | Oncogenic | Antibiotics | 107 | |
| Klebsiella pneumoniae | Colorectal cancer and liver metastasis | Unknown | 96 | ||
| Porphyromonas gingivalis | Colorectal cancer | Unknown | 96 | ||
| Prevotella denticola | Colorectal cancer | Unknown | 96 | ||
| Streptococcus anginosus | Colorectal cancer | Unknown | 96 | ||
| Streptococcus pneumoniae | Colorectal cancer | Unknown | 96 | ||
| Fungi | Ascomycota | Pancreatic ductal adenocarcinoma | Unknown | 111 | |
| Basidiomycota | Pancreatic ductal adenocarcinoma | Unknown | 111 | ||
| Candida albicans | Renal cell carcinoma; squamous cell carcinom | Oncogenic | 109 | ||
| Malassezia globosa | Pancreatic ductal adenocarcinoma | Oncogenic | 111 | ||
| Protozoa | Toxoplasma gondii | Brain, lung, prostate, cervix, and endometrial cancers | Oncogenic | Anti-Toxoplasma drugs | 112 |