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. 2022 Mar 14;12(6):2833–2859. doi: 10.7150/thno.70719

Table 4.

Phages applied for cancer diagnosis and therapy.

Phages Technology/Mechanism Diagnosis/Monitor Therapy
M13 (e.g. M13mp19 116, 119, M13KO7 30, 117, 124, 192, etc.; T4 32; T7 46; fd phage 122; fd-tet 123 Page display Screen Oligopeptides 116, antigen binding fragment 117 and gene-specific affibody 192 for cancer targeting imaging and diagnosis Screen peptides for targeted therapy of cancer 119; Generating gene-targeting agents for cancer therapy 30; Generating monoclonal antibody for cancer chemotherapy 124; Generating vaccines;32, 46 Guiding the delivery of small interfering RNA (siRNA) for cancer gene therapy;123 Acting as immunomodulators 193 in vivo