Table 5.
Oncolytic virus | Technology/Mechanism | Diagnosis/ Therapy |
---|---|---|
Adenovirus 133-135; HSV-1 136; Measles virus 137; Newcastle disease virus 53; Parvovirus 138; Vaccinia virus 139; VSV 140-142 | Adding luciferase genes, fluorescent proteins or radio-labelled substrates into virus | Bioluminescence imaging, fluorescence imaging and nuclear medicine-based imaging 51 |
Adenovirus 52; HSV-1 136; Measles virus 137; Newcastle disease virus 53; Poliovirus 138; Vaccinia virus 145; VSV 140-142; Reovirus 194 | Anti-proliferation, anti-apoptosis and immune modulators; Vectors for gene therapy | Acting as an oncolytic agent 50, 145; Applied for cancer immunotherapy 144; Delivery of molecules, siRNA and shRNA for cancer gene therapy 52, 146 |