Figure 18.
CDs-based cancer therapy by NO-based phototherapeutic. (A) The schematic diagram of microenvironment-independent NO-based phototherapeutic nanoplatform. (B) NO generation in hypoxia and normoxia; (C) ESR spectra of g-C3N4 (with O2) and ArgCCN (with or without O2) under irradiation. (D) NO generation in the presence of various scavengers. (E) CLSM images of intracellular NO generation. (F) Fluorescence images of intracellular O2 content probe in MCF-7 cells treated with PBS only or CCN+laser, poly-L-arginine+laser, ArgCCN and ArgCCN+laser. Adapted with permission from 231, copyright 2020 Wiley-VCH GmbH.