CDs-based targeted bioimaging through selective recognition. (A) Schematic illustration of the formation of PEI-CDs/HA-Dox, and the nanoprobe used for targeted cancer cell imaging and drug delivery. Adapted with permission from 198, copyright 2017 Elsevier B.V. (B) Schematic of molecularly imprinted polymer coated CDs for cancer cell targeting bioimaging, (C) Confocal microscope images of fixed HaCaT and HeLa cells treated with CDs, CD-NIP, and CD-MIPGlcA. (D) Confocal micrographs showing labeling of GlcA on a single HeLa cell by CD-MIPGlcA (green) and nuclear staining with PI (red). (E) Analysis of labeled cells with CD-MIPGlcA, CDNIP, and CD as obtained from Image J by measuring the normalized fluorescence of each single cell area from five different images. Adapted with permission from 199, copyright 2018 American Chemical Society.