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. 2022 Mar 11;4(2):e210067. doi: 10.1148/rycan.210067

Figure 5:

Comparison of static standardized uptake value (SUV) and standard Patlak (sPatlak)–derived parametric images in a representative examination from group A. This 72-year-old woman with a history of right cavernous sinus meningioma who underwent gamma knife radiosurgery 12 years prior presented with an avidly enhancing soft-tissue mass involving the right cavernous sinus, not well delineated on (A) T1-weighted postcontrast images alone. (B) Static PET image summed over the entire 50-minute acquisition period and (C) PET/MRI fusion image demonstrate markedly improved delineation of the tumor. (D) Static PET image from the last 10 minutes of acquisition (50–60 minutes after injection), along with (E) Patlak slope Ki and (F) Patlak intercept Vb parametric images from the same PET/MRI examination. The color bars are to maximum SUV for C and D, from 0 to maximum Ki (0–0.4 mL of reference tissue/min/grams of targeted tissue) for E, and from 0 to maximum Vb (0–11 mL of reference tissue/grams of targeted tissue) for F. Ki = net binding rate constant, Vb = sum of blood volume fraction and distribution volume.

Comparison of static standardized uptake value (SUV) and standard Patlak (sPatlak)–derived parametric images in a representative examination from group A. This 72-year-old woman with a history of right cavernous sinus meningioma who underwent gamma knife radiosurgery 12 years prior presented with an avidly enhancing soft-tissue mass involving the right cavernous sinus, not well delineated on (A) T1-weighted postcontrast images alone. (B) Static PET image summed over the entire 50-minute acquisition period and (C) PET/MRI fusion image demonstrate markedly improved delineation of the tumor. (D) Static PET image from the last 10 minutes of acquisition (50–60 minutes after injection), along with (E) PatlakslopeKi and (F) Patlak interceptVb parametric images from the same PET/MRI examination. The color bars are to maximum SUV for C and D, from 0 to maximum Ki (0–0.4 mL of reference tissue/min/grams of targeted tissue) for E, and from 0 to maximum Vb (0–11 mL of reference tissue/grams of targeted tissue) for F. Ki = net binding rate constant, Vb = sum of blood volume fraction and distribution volume.