Table 1.
Lung tissue cytokines in wild-type BALB/c mice exposed to saline or LPS.
| Saline-exposed mice (n = 8) | LPS-exposed mice (n = 8) | p-value | |
|---|---|---|---|
| IL-1β | 0.64 (0.49 – 1.53) | 51.6 (11.5 – 90.7) | <0.0001 |
| IL-6 | 0 (0 – 0.02) | 7.8 (1.75 – 20.9) | 0.0001 |
| TNF-⍺ | 0.07 (0.05 – 0.12) | 2.52 (0.49 – 6.36) | <0.0001 |
| IL-33 | 55 (10 – 72.3) | 3915 (57.5 – 9990) | 0.258 |
| IFN-γ | 0 (0 – 0) | 53 (16 – 173) | <0.0001 |
| IL-13 | 0 (0 – 0) | 0.81 (0.36 – 1.08) | <0.0001 |
| IL-17A | 1.5 (1.1 – 5.1) | 77 (12 – 107) | 0.0079 |
| IL-22 | 1.17 (0 – 5.2) | 16.8 (4.57 – 88.28) | 0.0095 |
| KC | 1.12 (0.86 – 1.61) | 16.57 (5.49 – 27.58) | 0.0001 |
| MIP-2 | 0.53 (0.44 – 1.42) | 16 (2.5 – 33.6) | 0.0001 |
| GM-CSF | 0.2 (0.19 – 0.4) | 13 (7 – 17) | 0.0002 |
Values are represented as pg per mg lung tissue and as median with 25 and 75 percentiles between brackets. The Mann – Whitney test was used to compare both groups.