Table 2.
Diagnostic ability of different test modalities for patients with IE.
| Test modality | Sensitivity | Specificity | Positive predict value | Negative predict value |
ROC AUC |
ROC P |
|---|---|---|---|---|---|---|
| Blood culture | 29.3% (0.21–0.39) |
100% (0.72–1.00) |
100% (0.88–1.00) |
13.6% (0.07–0.23) |
0.646 (0.601–0.691) |
0.112 |
| Valve culture | 16.2% (0.10–0.25) |
100% (0.72–1.00) |
100% (0.79–1.00) |
11.7% (0.06–0.20) |
0.581 (0.544–0.617) |
0.381 |
| Valve NGS | 85.9% (0.77–0.92) |
72.7% (0.39–0.94) |
96.6% (0.90–0.99) |
36.4% (0.17–0.59) |
0.793 (0.651–0.935) |
0.001 |
| Combined detection | 89.9% (0.82–0.95) |
72.7% (0.39–0.94) |
96.7% (0.91–0.99) |
44.4% (0.22–0.69) |
0.813 (0.672–0.954) |
0.001 |