Table 1.

Association of positive airway pressure with cardiovascular events and deaths in the randomized clinical trials.

	Positive airway pressure		Control		Risk ratio
	Events or deaths, No.	Participants, No.	Events or deaths, No.	Participants, No.	(95% CI)
Major adverse cardiovascular events
Barbé et al. (19)	6	357	10	366	0.62 (0.23–1.67)
Peker et al. (20)	17	122	21	122	0.81 (0.45–1.46)
McEvoy et al. (21)	134	1,359	127	1,358	1.05 (0.84–1.33)
Major adverse cardiovascular events plus
Barbé et al. (19)	23	357	21	366	1.12 (0.63–1.99)
Peker et al. (20)	47	122	53	122	0.89 (0.66–1.20)
McEvoy et al. (21)	233	1,359	217	1,358	1.07 (0.91–1.27)
Cardiovascular deaths
Barbé et al. (19)	1	357	0	366	3.08 (0.13–75.24)
Peker et al. (20)	3	122	7	122	0.43 (0.11–1.62)
McEvoy et al. (21)	25	1,359	20	1,358	1.25 (0.70–2.24)
All-cause death
Barbé et al. (19)	8	357	3	366	2.73 (0.73–10.22)
Peker et al. (20)	7	122	9	122	0.78 (0.30–2.02)
McEvoy et al. (21)	40	1,359	43	1,358	0.93 (0.61–1.42)
Non-Cardiovascular deaths
Barbé et al. (19)	7	357	13	366	0.55 (0.22–1.37)
Peker et al. (20)	4	122	2	122	2.00 (0.37–10.72)
McEvoy et al. (21)	15	1,359	23	1,358	0.65 (0.34–1.24)
Acute coronary syndromes
Barbé et al. (19)	2	357	8	366	0.26 (0.05–1.20)
Peker et al. (20)	11	122	8	122	1.38 (0.57–3.30)
McEvoy et al. (21)	42	1,359	39	1,358	1.08 (0.70–1.65)
Stroke
Barbé et al. (19)	3	357	2	366	1.54 (0.26–9.15)
Peker et al. (20)	3	122	6	122	0.50 (0.13–1.95)
McEvoy et al. (21)	67	1,359	68	1,358	0.98 (0.71–1.37)
Hospitalization for unstable angina
Barbé et al. (19)	17	357	11	366	1.58 (0.75–3.34)
McEvoy et al. (21)	99	1,359	5	659	1.10 (0.83–1.45)
Heart failure
Barbé et al. (19)	3	357	5	366	0.62 (0.15–2.55)
Peker et al. (20)	30	122	32	122	0.94 (0.61–1.44)
McEvoy et al. (21)	17	1,359	17	1,358	1.00 (0.51–1.95)