Table 2.
The association of clinical outcome of GBM patients with immune cell infiltration and the AlkB family gene expression by applying the multivariable Cox proportional hazard model from the TIMER database.
| coef | HR | 95%CI_I | 95%CI_u | P value | sig | |
|---|---|---|---|---|---|---|
| B cell | 0.388 | 1.474 | 0.235 | 9.258 | 0.679 | |
| CD8_Tcel | 0.512 | 1.668 | 0.485 | 5.734 | 0.417 | |
| CD4_Tcell | 3.261 | 26.088 | 2.421 | 281.060 | 0.007 | ** |
| Macrophage | -1.035 | 0.355 | 0.026 | 4.917 | 0.440 | |
| Neutrophil | -1.396 | 0.248 | 0.011 | 5.712 | 0.383 | |
| Dendritic | 2.075 | 7.967 | 2.265 | 28.029 | 0.001 | ** |
| ALKBH1 | -0.008 | 0.992 | 0.485 | 2.032 | 0.983 | |
| ALKBH2 | -0.175 | 0.839 | 0.390 | 1.807 | 0.655 | |
| ALKBH3 | 0.189 | 1.208 | 0.606 | 2.408 | 0.591 | |
| ALKBH4 | 0.973 | 2.646 | 1.279 | 5.475 | 0.009 | ** |
| ALKBH5 | 0.147 | 1.158 | 0.585 | 2.293 | 0.674 | |
| ALKBH6 | 0.821 | 2.272 | 1.211 | 4.260 | 0.011 | * |
| ALKBH7 | -0.115 | 0.891 | 0.444 | 1.789 | 0.746 | |
| ALKBH8 | -0.869 | 0.419 | 0.190 | 0.927 | 0.032 | * |
| FTO | 0.045 | 1.047 | 0.492 | 2.226 | 0.906 |
*p < 0.05, **p < 0.01.