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. 2022 Mar 10;12:847821. doi: 10.3389/fonc.2022.847821

Table 2.

The association of clinical outcome of GBM patients with immune cell infiltration and the AlkB family gene expression by applying the multivariable Cox proportional hazard model from the TIMER database.

coef HR 95%CI_I 95%CI_u P value sig
B cell 0.388 1.474 0.235 9.258 0.679
CD8_Tcel 0.512 1.668 0.485 5.734 0.417
CD4_Tcell 3.261 26.088 2.421 281.060 0.007 **
Macrophage -1.035 0.355 0.026 4.917 0.440
Neutrophil -1.396 0.248 0.011 5.712 0.383
Dendritic 2.075 7.967 2.265 28.029 0.001 **
ALKBH1 -0.008 0.992 0.485 2.032 0.983
ALKBH2 -0.175 0.839 0.390 1.807 0.655
ALKBH3 0.189 1.208 0.606 2.408 0.591
ALKBH4 0.973 2.646 1.279 5.475 0.009 **
ALKBH5 0.147 1.158 0.585 2.293 0.674
ALKBH6 0.821 2.272 1.211 4.260 0.011 *
ALKBH7 -0.115 0.891 0.444 1.789 0.746
ALKBH8 -0.869 0.419 0.190 0.927 0.032 *
FTO 0.045 1.047 0.492 2.226 0.906

*p < 0.05, **p < 0.01.