Fig 3.

Risk of detecting histological cervical intraepithelial neoplasia (CIN) grade 2 or worse, CIN grade 3 or worse, cancer, and frankly invasive cancer among women attending for colposcopy, by reason for referral and age group. Results are restricted to women aged 25-69, as different management is recommended for women aged 70-74 undergoing exit testing. HPV16/18+=positive for human papillomavirus (HPV) types 16/18 at baseline screening test. Triage+=positive for HPV types not 16/18 with atypical squamous cells-cannot exclude high grade squamous intraepithelial lesion (ASC-H) or worse or glandular liquid based cytology result. 12 month follow-up (HPV16/18+ or HPV not 16/18 and ASC-H+)=12 month test result is HPV positive, and either positive for HPV16/18 or ASC-H or worse or glandular abnormality on liquid based cytology, or both. 12 month follow-up (HPV not 16/18 and ≤LSIL (low grade squamous intraepithelial lesion))=12 month test result is HPV types not 16/18 positive and liquid based cytology result is negative or ASC-US (atypical squamous cells of undetermined significance) or LSIL. ASC-H+=liquid based cytology result of ASC-H, high grade squamous intraepithelial lesion or more severe abnormality or any glandular abnormality. See supplementary tables A17 and A18 for data supporting this figure