Table 2.
Anthropomorphic, symptom, test result, and given variables. Comparison between the PCOSa-positive group and the PCOS-negative group with P values (N=526).
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All women (N=526) | PCOS-positive size (n=170) | PCOS-negative size (n=356) | P valueb | |||||||
| Anthropomorphic variables, median (IQR) | |||||||||||
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BMI | 24.27 (21.69 to 26.66) | 25.1 (26.25 to 33) | 23.61 (21.37 to 26.13) | <.001 | ||||||
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Height (cm) | 156 (152 to 160) | 158 (152 to 161) | 156 (152 to 160) | .12 | ||||||
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Hip (inches) | 38 (36 to 40) | 39 (36 to 42) | 38 (36 to 40) | <.001 | ||||||
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Waist circumference (inches) | 34 (52 to 65) | 35 (32 to 37) | 34 (31.75 to 35) | <.001 | ||||||
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Waist-to-hip ratio | 0.89 (0.88 to 0.93) | 0.89 (0.86 to 0.93) | 0.89 (0.86 to 0.93) | .91 | ||||||
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Weight (kg) | 59 (52 to 65) | 62 (55 to 70) | 58 (52 to 64) | <.001 | ||||||
| Symptom variables | |||||||||||
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Acanthosis nigricans (%) | 158 (30) | 105 (61.8) | 53 (14.9) | <.001 | ||||||
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Acne (%) | 256 (48.7) | 118 (69.4) | 138 (38.8) | <.001 | ||||||
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Hair loss (%) | 236 (44.9) | 97 (57.1) | 139 (39) | <.001 | ||||||
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Hirsutism (%) | 143 (27.2) | 22 (12.9) | 46 (12.9) | <.001 | ||||||
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Irregular menstrual cycle (%) | 146 (27.8) | 91 (53.5) | 55 (15.5) | <.001 | ||||||
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Length of menstrual cycle (days), median (IQR) | 5 (5 to 5) | 5 (3 to 5) | 5 (5 to 6) | <.001 | ||||||
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Weight gain (%) | 199 (37.8) | 117 (68.8) | 82 (23) | <.001 | ||||||
| Test result variables, median (IQR) | |||||||||||
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AMHc,d (ng/mL) | 1.31 (0.70 to 1.92) | 1.74 (0.88 to 2.32) | 1.16 (0.65 to 1.66) | <.001 | ||||||
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Antral follicles in left ovary | 5 (3 to 9) | 10 (7 to 12) | 4 (2 to 6) | <.001 | ||||||
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Antral follicles in right ovary | 6 (3 to 10) | 11 (8 to 13) | 4 (2 to 7) | <.001 | ||||||
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Average follicle size left ovary (mm) | 15 (13 to 18) | 16 (14 to 18) | 15 (13 to 18) | .02 | ||||||
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Average follicle size right ovary (mm) | 16 (13 to 18) | 16 (14 to 18) | 15.5 (13 to 18) | .046 | ||||||
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Diastolic BP (mm Hg) | 80 (70 to 80) | 80 (70 to 80) | 80 (70 to 80) | .69 | ||||||
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Endometrium thickness (mm) | 8.5 (7 to 9.8) | 8.9 (7.6 to 10) | 8.3 (7 to 9.5) | .006 | ||||||
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FSHc,e (mIU/mL) | 1.58 (1.2 to 1.85) | 1.51 (1.17 to 1.75) | 1.61 (1.25 to 1.88) | .007 | ||||||
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FSH to LHf ratioc | 0.77 (0.35 to 1.35) | 0.69 (0.07 to 1.14) | 0.86 (0.44 to 1.41) | .002 | ||||||
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Glycated hemoglobin level (g/100 ml) | 11 (10.5 to 11.7) | 11.05 (10.7 to 11.9) | 11 (10.5 to 11.5) | .03 | ||||||
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HCGg Ic (mIU/mL) | 2.96 (0.688 to 5.7) | 4.25 (0.69 to 5.85) | 2.68 (0.69 to 5.62) | .10 | ||||||
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HCG IIc (mIU/mL) | 0.69 (0.688 to 4.61) | 0.69 (0.69 to 4.63) | 0.69 (0.69 to 4.59) | .94 | ||||||
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LH (mIU/mL) | 2.25 (1.03 to 3.68) | 2.23 (1.03 to 4.31) | 2.3 (1.03 to 3.6) | .25 | ||||||
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PRGc,h (ng/mL) | −1.14 (−1.39 to −0.78) | −1.14 (−1.39 to −0.84) | −1.17 (−1.39 to −0.78) | .54 | ||||||
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PRLc,i (ng/mL) | 3.09 (2.68 to 3.39) | 3.13 (2.64 to 3.41) | 3.06 (2.69 to 3.39) | .73 | ||||||
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Pulse rate (beats/min) | 72 (72 to 74) | 72.5 (72 to 74) | 72 (72 to 74) | .002 | ||||||
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Random glucose test (mg/100 mL) | 100 (92 to 107) | 100 (92 to 107) | 97.5 (92 to 108) | .32 | ||||||
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Respiratory rate (breaths/min) | 18 (18 to 20) | 20 (18 to 20) | 18 (18 to 20) | .28 | ||||||
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Systolic BPj (mm Hg) | 110 (110 to 120) | 110 (110 to 120) | 110 (110 to 120) | .73 | ||||||
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Thyrotropinc (mIU/L) | 0.82 (0.39 to 1.27) | 0.84 (0.39 to 1.26) | 0.78 (0.39 to 1.27) | .69 | ||||||
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Vitamin D3 (ng/mL) | 25.95 (20.73 to 34.48) | 25.38 (19.3 to 33.58) | 26.3 (21.28 to 35.8) | .19 | ||||||
| Given variables | |||||||||||
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Age (years), median (IQR) | 31 (27 to 35) | 29 (26.25 to 33) | 32 (28 to 36) | <.001 | ||||||
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Blood type (%) | .97 | |||||||||
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A+ | 105 (20) | 33 (19.4) | 72 (20.2) |
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A− | 13 (2.5) | 4 (2.4) | 9 (2.5) |
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B+ | 130 (24.7) | 40 (23.5) | 90 (25.3) |
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B− | 16 (3) | 6 (3.5) | 10 (2.8) |
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O+ | 200 (38) | 63 (37.1) | 137 (38.5) |
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O− | 19 (3.6) | 8 (4.7) | 11 (3.1) |
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AB+ | 41 (7.8) | 15 (8.8) | 26 (7.3) |
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AB- | 2 (0.4) | 1 (0.6) | 1 (0.3) |
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Married (years), median (IQR) | 7 (4 to 10) | 6 (3 to 9) | 7 (4 to 11) | .001 | ||||||
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Number of abortions (%) | .61 | |||||||||
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0 | 425 (80.8) | 141 (82.9) | 284 (79.8) |
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1 | 68 (12.9) | 21 (12.4) | 47 (13.2) |
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2 and above | 33 (6.3) | 8 (4.7) | 25 (7) |
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Fast food consumption (%) | 270 (51.3) | 134 (78.8) | 136 (38.2) | <.001 | ||||||
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Pregnant (%) | 204 (38.8) | 63 (37.1) | 141 (39.6) | .64 | ||||||
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Regular exercise (%) | 127 (24.1) | 48 (28.2) | 79 (22.2) | .16 | ||||||
aPCOS: polycystic ovary syndrome.
bP values were calculated by the Wilcoxon test for median comparison and chi-square test for proportion comparison.
cLog-transformed variables.
dAMH: anti-Müllerian hormone.
eFSH: follicle-stimulating hormone.
fLH: luteinizing hormone.
gHCG: human chorionic gonadotropin.
hPRG: progrestrone.
iPRL: prolactin.
jBP: blood pressure.