Fig. 7.

(A) Schematic illustration of spherical scaffolds implanted in the rabbit anophthalmic sock after enucleation. (B) The CAD models of two different graded pore structure design of spherical scaffolds. (C) Outward appearance and micro-CT reconstructed cross-section images of two different graded porous hardystonite implants and HA implant. (D) The surgical procedure of enucleation and orbital implantation. (E) Postoperative appearance of conjunctival sac (a, b, c) and harvest scaffolds (d, e, f) 4 weeks after implantation. Yellow dotted circles mark conjunctival sac wounds. (F) H&E staining of harvest scaffolds. (a–c) show different regions of the scaffolds. S: scaffolds. Yellow arrows point out newly formed blood vessels.