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AUCs of aciclovir in relationship to patient age. (a) Aciclovir (400 mg) given as a 1-h infusion (rs = 0.91, P < 0.0001); (b) oral administration of 400 mg of aciclovir (rs = 0.18, P = 0.59); (c) oral administration of 500 mg of valaciclovir (rs = 0.68, P = 0.015).
