Table 4.
Reversibility of the tumor cell dormancy-like phenotype. Cells were seeded on Mg and Mg–6Ag, detached and reseed on glass slides. Relative Ki-67 positive cells are shown as m±sd from two samples with three randomly chosen positions for each sample. Significance differences between relative Ki-67 positive cells on Mg or Mg–6Ag or their reseeded pairs were obtained via a Mann-Whitney test (n = 6); ** = p < 0001.
| relative Ki-67 positive cells |
||
|---|---|---|
| Saos-eGFP | RF Fibroblasts | |
| Mg | 8.2 ± 2.1 | 2.1 ± 2.7 |
| reseeded from Mg | 55.4 ± 10.5** | 0.0 ± 0.0 |
| Mg–6Ag | 2.7 ± 3.9 | 0.3 ± 0.4 |
| reseeded from Mg–6Ag | 55.2 ± 21.4** | 0.0 ± 0.0 |