Average enrichment factor at 1% (EF1) for each individual program calculated on the 34 benchmark targets, and the average fold increase of the ECR method over each program.

Average	ICM	rDock	Auto Dock 4	PLANTS
EF1	23.5	10.5	5.8	9.9
Fold increasea	1.4	3.4b	7.4c	3.2d

^aAverage value calculated as , where N is the number of targets.

^bThis value does not include XIAP and ANDR, which had EF = 0, and therefore make the average fold increase ≫ 100.

^cThis value does not include these five targets: HXK4, NRAM, XIAP, DYR and PNPH, which had EF = 0, and therefore make the average fold increase ≫ 100.

^dThis value does not include FABP4 and PYRD, which had EF = 0, and therefore make the average fold increase ≫ 100.