Table 2.

The regulation of miRNA in different CVDs.

Cardiovascular diseases	miRNA
	Up-regulation	Down-regulation
Cardiac hypertrophy	miR-208, miR-21, miR-29, miR-18b, miR-199, miR-23, miR-22 (125) miR-195 (126)	miR-1, miR-133, (125) miR-9 (127)
Cardiac arrhythmias	miR-1, miR-133, miR-708-5p, miR-217-5p, miR-208 (125)	miR-499-5p (125)
Cardiac fibrosis	miR-21, miR-15 (125)	miR-133, miR-29, miR-26a, miR-24, miR-590 (125)
Coronary artery diseases	miR-1, miR-21, miR-33, miR-208, (125) miR-25, miR-92a, miR-106b, miR-122, miR-133a, miR-135a, miR-140-3p, miR-146a, miR-155, miR-182, miR-186, miR-370, miR-451, miR-490-3p (81)	miR-133, miR-126-3p, miR-195, miR-145, miR-155, miR-17, miR-93-5p (125) miR-29a, miR-31, miR-125b, miR-147, miR-181a, miR-214, miR-320b (81)
Acute coronary syndromes	miR-1, miR-21, miR-30a, miR-30c, miR-34a, miR-122, miR-126, miR-133a, miR-133b, miR-134, miR-145, miR-146a, miR-155, miR-186, miR-195, miR-198, miR-199, miR-208, miR-223, miR-320a, miR-328, miR-370, miR-423-5p, miR-433, miR-485-3p, miR-499 (81)	Let-7b, miR-29a, miR-122, miR-125b, miR-126, miR-155, miR-223, miR-320b, miR-375, miR-663b, miR-1291 (81)
Heart failure	miR-199b, miR-24, miR-208, miR-125, miR-195, miR-214, miR-423-5p, miR-320a, miR-22, miR-92b, miR-122, miR-650, miR-662, miR-1228, miR-100, miR-342 (125) miR-18b, miR-21, miR-29b, miR-129-5p, miR-133a, miR-142-3p, miR-200b, miR-210, miR-499, miR-519e, miR-520d-5p, miR-622, miR-675, miR-1254 (81)	miR-126, miR-133, miR-1, miR-107, miR-3175, miR-583, miR-29b (125) miR-30b, miR-103, miR-125b, miR-139, miR-142-3p, miR-142-5p, miR-342-3p, miR-497 (81)