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. 2022 Mar 30;22:132. doi: 10.1186/s12872-022-02569-x

Table 3.

Relationship between amount of leisure-time and household physical activity and onset of circulatory disease

Men (n = 1343) Women (n = 2,398)
 ≤ 0.43 (METs-hr/day) 0.44–3.49 (METs-hr/day)  ≥ 3.50 (METs-hr/day)  ≤ 7.80 (METs-hr/day) 7.81–12.70 (METs-hr/day)  ≥ 12.71 (METs-hr/day)
n = 449 n = 447 n = 447 Trend test n = 800 n = 805 n = 793 Trend test
HR 95% CI P-value HR 95% CI P value P value HR 95% CI P value HR 95% CI P value P value
CVD 21 14 19 16 14 8
Sex and age adjusted model 1.00 (Ref) 0.76 (0.39–1.50) 0.433 0.93 (0.50–1.73) 0.811 0.796 1.00 (Ref) 1.04 (0.50–2.12) 0.926 0.48 (0.21–1.12) 0.089 0.102
Multivariable adjusted model 1.00 (Ref) 0.85 (0.41–1.79) 0.670 0.64 (0.28–1.43) 0.273 0.275 1.00 (Ref) 0.83 (0.34–2.00) 0.677 0.09 (0.02–0.50) 0.006 0.010
Stroke 17 10 14 13 12 7
Sex and age adjusted model 1.00 (Ref) 0.67 (0.30–1.46) 0.313 0.87 (0.43–1.77) 0.699 0.671 1.00 (Ref) 1.10 (0.50–2.42) 0.812 0.52 (0.21–1.30) 0.159 0.178
Multivariable adjusted model 1.00 (Ref) 0.82 (0.35–1.92) 0.644 0.50 (0.19–1.31) 0.156 0.159 1.00 (Ref) 0.96 (0.38–2.46) 0.937 0.08 (0.01–0.54) 0.010 0.019
Total(n = 3,741)
Sum of sex lowest tertiles Sum of sex middle tertiles Sum of sex highest tertiles
n = 1249 n = 1252 n = 1240 Trend test
HR 95% CI P-value HR 95% CI P value P value
CVD 37 28 27
Sex and age adjusted model 1.00 (Ref) 0.88 (0.54–1.44) 0.605 0.72 (0.44–1.19) 0.201 0.202
Multivariable adjusted model 1.00 (Ref) 0.91 (0.52–1.58) 0.730 0.40 (0.20–0.82) 0.012 0.015
Stroke 30 22 21
Sex and age adjusted model 1.00 (Ref) 0.85 (0.49–1.48) 0.568 0.70 (0.40–1.23) 0.215 0.214
Multivariable adjusted model 1.00 (Ref) 0.89 (0.48–1.65) 0.721 0.29 (0.13–0.68) 0.005 0.006

Sex and age adjusted model: Adjusted for sex and age

Multivariable adjusted model: sex and age adjusted model + adjusted for smoking (currently, past, never), drinking (currently, past, never, job (y/n), BMI, hypertension (y/n), dyslipidemia(y/n), diabetes (y/n), and physical activity other than during leisure time (sleep, job, transportation, other)

CVD cardiovascular disease; BMI body mass index; MET metabolic equivalent; HR hazard ratio; CI confidence interval