Table 1.
Significant Linear Regression Models by Substance
| Parameters | Model | E-Values | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cancer | Substance | Estimate | Std.Error | t-Statistic | P-Value | R.Squared | Adj.R.Squared | Sigma | t-Statistic | P-Value | E-Value—Point | E-Value—Lower |
| All_Cancer | Cigarettes | 311.2758 | 26.2010 | 11.8803 | 6.10E-30 | 0.1587 | 0.1576 | 30.2276 | 141.1415 | 6.10E-30 | 2.35E + 04 | 5.02E + 03 |
| All_Cancer | AUD | 174.3105 | 77.5060 | 2.2490 | 0.0248 | 0.0067 | 0.0054 | 32.8455 | 5.0580 | 0.0248 | 249.76 | 3.16 |
| Cervix | Analgesics | 14.2232 | 2.9928 | 4.7525 | 2.41E-06 | 0.0293 | 0.0280 | 0.7557 | 22.5865 | 2.41E-06 | 5.49E + 07 | 4.76E + 04 |
| Ovary | Analgesics | 13.0281 | 3.4213 | 3.8079 | 1.52E-04 | 0.0190 | 0.0177 | 0.8639 | 14.5002 | 1.52E-04 | 1.82E + 06 | 1.58E + 03 |
| Lung | Analgesics | 156.2452 | 47.8675 | 3.2641 | 0.0011 | 0.0140 | 0.0127 | 12.0870 | 10.6545 | 0.0011 | 2.57E + 05 | 222.51 |
| Prostate | AUD | 294.0806 | 26.9078 | 10.9292 | 6.73E-26 | 0.1377 | 0.1365 | 11.4030 | 119.4472 | 6.73E-26 | 3.11E + 10 | 4.67E + 08 |
| Ovary | AUD | 16.4306 | 1.9686 | 8.3461 | 3.40E-16 | 0.0852 | 0.0840 | 0.8343 | 69.6578 | 3.40E-16 | 1.21E + 08 | 1.82E + 06 |
| Colorectal | AUD | 116.6256 | 14.8666 | 7.8448 | 1.50E-14 | 0.0760 | 0.0748 | 6.3002 | 61.5409 | 1.50E-14 | 4.14E + 07 | 6.21E + 05 |
| Bladder | AUD | 59.4761 | 7.6578 | 7.7668 | 2.65E-14 | 0.0746 | 0.0734 | 3.2452 | 60.3227 | 2.65E-14 | 3.50E + 07 | 5.25E + 05 |
| CLL | AUD | 13.3118 | 2.7643 | 4.8156 | 1.78E-06 | 0.0301 | 0.0288 | 1.1714 | 23.1903 | 1.78E-06 | 6.19E + 04 | 928.09 |
| Hodgkins | AUD | 5.4767 | 1.1398 | 4.8051 | 1.87E-06 | 0.0299 | 0.0286 | 0.4830 | 23.0892 | 1.87E-06 | 6.06E + 04 | 907.37 |
| Esophagus | AUD | 8.1151 | 2.0465 | 3.9653 | 8.06E-05 | 0.0214 | 0.0201 | 0.8377 | 15.7240 | 8.06E-05 | 1.35E + 04 | 173.64 |
| NH_Lymphoma | AUD | 17.1252 | 4.6200 | 3.7067 | 2.25E-04 | 0.0180 | 0.0167 | 1.9579 | 13.7398 | 2.25E-04 | 5.73E + 03 | 85.34 |
| Thyroid | Cannabis | 38.1264 | 3.6137 | 10.5504 | 2.35E-24 | 0.1295 | 0.1284 | 2.9671 | 111.3120 | 2.35E-24 | 2.40E + 05 | 2.74E + 04 |
| Liver | Cannabis | 18.7374 | 1.9860 | 9.4349 | 4.82E-20 | 0.1064 | 0.1052 | 1.6306 | 89.0176 | 4.82E-20 | 6.96E + 04 | 7.96E + 03 |
| Breast | Cannabis | 38.4836 | 5.4934 | 7.0054 | 5.50E-12 | 0.0616 | 0.0603 | 4.5104 | 49.0761 | 5.50E-12 | 4.71E + 03 | 538.42 |
| Bladder | Cannabis | 25.5306 | 4.0013 | 6.3805 | 3.09E-10 | 0.0516 | 0.0503 | 3.2853 | 40.7110 | 3.09E-10 | 2.36E + 03 | 269.10 |
| Pancreas | Cannabis | 6.9457 | 1.5165 | 4.5800 | 5.44E-06 | 0.0273 | 0.0260 | 1.2451 | 20.9766 | 5.44E-06 | 319.83 | 36.14 |
| AML | Cannabis | 2.7773 | 0.6876 | 4.0389 | 5.92E-05 | 0.0213 | 0.0200 | 0.5646 | 16.3128 | 5.92E-05 | 175.35 | 19.61 |
| Lung | Cigarettes | 206.6791 | 7.3636 | 28.0678 | 5.75E-119 | 0.5130 | 0.5123 | 8.4952 | 787.7991 | 5.75E-119 | 8.24E + 09 | 1.76E + 09 |
| Colorectal | Cigarettes | 102.7662 | 4.2610 | 24.1177 | 1.60E-95 | 0.4375 | 0.4367 | 4.9159 | 581.6646 | 1.60E-95 | 3.65E + 08 | 7.81E + 07 |
| Cervix | Cigarettes | 8.1118 | 0.5950 | 13.6326 | 5.88E-38 | 0.1990 | 0.1979 | 0.6865 | 185.8480 | 5.88E-38 | 9.36E + 04 | 2.00E + 04 |
| Prostate | Cigarettes | 92.4997 | 10.0923 | 9.1653 | 4.68E-19 | 0.1010 | 0.0998 | 11.6433 | 84.0036 | 4.68E-19 | 2.76E + 03 | 589.25 |
| Vulva.&.Vagina | Cigarettes | 2.8291 | 0.3193 | 8.8614 | 6.79E-18 | 0.1031 | 0.1018 | 0.3601 | 78.5253 | 6.79E-18 | 2.54E + 03 | 524.66 |
| Ovary | Cigarettes | 5.6544 | 0.7272 | 7.7751 | 2.50E-14 | 0.0748 | 0.0735 | 0.8390 | 60.4529 | 2.50E-14 | 921.01 | 196.48 |
| Kidney | Cigarettes | 10.5734 | 1.7983 | 5.8796 | 6.19E-09 | 0.0442 | 0.0429 | 2.0747 | 34.5703 | 6.19E-09 | 206.12 | 43.66 |
| Penis | Cigarettes | 0.5348 | 0.1174 | 4.5549 | 6.90E-06 | 0.0476 | 0.0453 | 0.1023 | 20.7467 | 6.90E-06 | 231.92 | 29.65 |
| Brain | Cigarettes | 3.1188 | 0.7234 | 4.3113 | 1.84E-05 | 0.0242 | 0.0229 | 0.8346 | 18.5875 | 1.84E-05 | 59.47 | 12.30 |
| Bladder | Cigarettes | 11.8284 | 2.8920 | 4.0901 | 4.78E-05 | 0.0219 | 0.0206 | 3.3364 | 16.7287 | 4.78E-05 | 49.86 | 10.24 |
| Oropharynx | Cigarettes | 4.6826 | 1.1454 | 4.0882 | 4.82E-05 | 0.0219 | 0.0205 | 1.3214 | 16.7133 | 4.82E-05 | 49.79 | 10.22 |
| Hodgkins | Cigarettes | 1.0813 | 0.4232 | 2.5549 | 0.0108 | 0.0087 | 0.0073 | 0.4883 | 6.5277 | 0.0108 | 14.49 | 2.59 |
| Esophagus | Cigarettes | 1.6896 | 0.7647 | 2.2095 | 0.0275 | 0.0068 | 0.0054 | 0.8440 | 4.8819 | 0.0275 | 11.84 | 1.77 |
| Stomach | Cocaine | 45.7579 | 6.4211 | 7.1262 | 2.43E-12 | 0.0636 | 0.0623 | 1.2139 | 50.7829 | 2.43E-12 | 1.58E + 15 | 1.29E + 11 |
| Ovary | Cocaine | 27.1820 | 4.5057 | 6.0328 | 2.53E-09 | 0.0464 | 0.0451 | 0.8518 | 36.3948 | 2.53E-09 | 8.18E + 12 | 6.66E + 08 |
| Breast | Cocaine | 126.7521 | 24.1889 | 5.2401 | 2.09E-07 | 0.0354 | 0.0341 | 4.5728 | 27.4586 | 2.09E-07 | 1.80E + 11 | 1.47E + 07 |
| Kaposi | Cocaine | 14.8095 | 4.4075 | 3.3601 | 8.98E-04 | 0.0422 | 0.0385 | 0.4019 | 11.2900 | 8.98E-04 | 7.32E + 14 | 2.43E + 06 |
| Bladder | Cocaine | 84.8740 | 17.5732 | 4.8298 | 1.66E-06 | 0.0302 | 0.0289 | 3.3221 | 23.3265 | 1.66E-06 | 2.50E + 10 | 2.04E + 06 |
| Prostate | Cocaine | 225.7327 | 64.4301 | 3.5035 | 4.86E-04 | 0.0161 | 0.0148 | 12.1802 | 12.2747 | 4.86E-04 | 4.22E + 07 | 3.44E + 03 |
| Melanoma | Cocaine | 21,958.5719 | 7636.0557 | 2.8756 | 0.0041 | 0.0109 | 0.0096 | 1443.5593 | 8.2693 | 0.0041 | 2.05E + 06 | 166.80 |
| Hodgkins | Cocaine | 5.5031 | 2.5863 | 2.1278 | 0.0337 | 0.0060 | 0.0047 | 0.4889 | 4.5275 | 0.0337 | 5.61E + 04 | 4.00 |
| Colorectal | Cocaine | 65.7878 | 34.5865 | 1.9021 | 0.0575 | 0.0048 | 0.0035 | 6.5384 | 3.6181 | 0.0575 | 1.89E + 04 | 1.00 |