TABLE 3.

Linear regression results for the expression levels of CHRM1 and genes commonly mutated in colon cancer.

	Beta coefficient	Standard error	Degrees of freedom	t-value	p-value
Intercept	0.1752	0.1303	38	1.3444	0.1868
APC levels	0.2714	0.7273E-01	38	3.7313	6.2110E-04
Intercept	1.9058	0.3745	38	5.0886	1.0062E-05
CTNNB1 levels	−0.1985	0.5898E-01	38	−3.3660	1.7553E-03
Intercept	0.70369E-01	0.1978	38	0.3558	0.7239
SMAD4 levels	0.2415	0.8159E-01	38	2.9597	5.2787E-03

Univariate linear mixed models with participant id incorporated a random factor generated to model the relationship between CHRM1 and APC, CTNNB1, and SMAD4 levels were statistically significant. FPKM normalized and processed (log2 transformed, low count filtered, quantile normalized, and SVAseq batch corrected) expression levels were used for model generation.