Table 2.
nsSNPs and fsIndels in genes conferring resistance to CLA
| Gene | Nucleotide change | No. among CLA-R (n = 18) | No. among CLA-S (n = 94) | P |
|---|---|---|---|---|
| 23S rRNA | SNP | |||
| A2143G | 17 (94.44%) | 2 (2.13%) | < 0.0001 | |
| A2142G | 2 (11.11%) | 0 (0.00%) | 0.0250 | |
| T2182C | 6 (33.33%) | 31 (32.98%) | 0.9770 | |
| C148T | 2 (11.11%) | 0 (0.00%) | 0.0250 | |
| T1025C | 0 (0.00%) | 1 (1.06%) | 1.0000 | |
| G1027A | 14 (77.78%) | 52 (55.32%) | 0.0760 | |
| Indel | ||||
| 761delAA (GAA to G) | 16 (88.89%) | 84 (89.36%) | 1.0000 | |
| 762_763insT (A to AT) | 5 (27.78%) | 50 (53.19%) | 0.0482 | |
| 764_765insTTT (C to CTTT) | 8 (44.44%) | 54 (57.45%) | 0.3093 | |
| 1036_1037insC (A to AC) | 18 (100.00%) | 94 (100.00%) | 1.0000 | |
| 1515_1516insT (C to CT) | 3 (16.67%) | 9 (9.57%) | 0.4054 | |
| No change | 0 (0.00%) | 13 (13.83%) | 0.1232 |