Table 3.
Results of univariable biniary and multivariable logistic regression analyses of variables with possible influence on 10% impairment of the postoperative eGFR
| Variables | Univariable binary logistic regression | Multivariable logistic regression | ||
|---|---|---|---|---|
| p value | OR (95%-CI) | p value | OR (95%-CI) | |
| Preoperative variables | ||||
| Chemotherapy on primary tumor (Ref. yes) | 0.992 | 1.003 (0.610–1.649) | Not included | |
| Development of CRLM (Ref. metachronous) | 0.375 | 0.808 (0.504–1.295) | ||
| Age at liver resection (years) | 0.005 | 1.034 (1.010–1.058) | 0.085 | Not applicable |
| Number of CRLM | 0.590 | 1.029 (0.928–1.139) | Not included | |
| Size of CRLM | 0.175 | 0.995 (0.987–1.002) | 0.140 | Not applicable |
| Preoperative hemoglobin | 0.858 | 0.987 (0.852–1.142) | Not included | |
| Preoperative platelets | 0.548 | 1.001 (0.998–1.003) | ||
| Preoperative quick | 0.901 | 1.001 (0.984–1.018) | ||
| Preoperative eGFR < 90 ml/min (Ref. normal values) | < 0.001 | 2.466 (1.502–4.050) | 0.001 | 2.477 (1.478–4.151) |
| Intra- and postoperative variables | ||||
| Extent of liver resection (Ref. minor) | 0.728 | 1.086 (0.682–1.729) | Not included | |
| Operative duration > 120 min (Ref. no) | 0.116 | 1.003 (0.999–1.006) | 0.548 | Not applicable |
| Use of Pringle maneuver (Ref. not used) | 0.963 | 1.012 (0.614–1.668) | Not included | |
| Weight of liver specimen in g | 0.529 | 1.000 (0.999–1.000) | ||
| Overall transfusion of > 2 units PRBC (Ref. no) | 0.051 | 1.586 (0.998–2.522) | 0.046 | 1.638 (1.010–2.657) |
| Postoperative complications graded Dindo-Clavien > 3 (Ref. no) | 0.068 | 1.742 (0.961–3.157) | 0.451 | Not applicable |
| ICU-stay (days) | 0.298 | 1.017 (0.986–1.048) | 0.790 | |
OR Odds ratio, CI Confidence intervall