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. 2022 Mar 16;10:867949. doi: 10.3389/fcell.2022.867949

FIGURE 1.

FIGURE 1

Experimental outline for challenge with diisopropylfluorophosphate (DFP). (A) Male and female rats were injected with 4–5 mg/kg DFP (s.c.) followed immediately by 2 mg/kg atropine sulfate (ATS, i.m.) and 25 mg/kg 2-PAM (i.m.). One hour later, behavioral seizures were terminated with 3 mg/kg midazolam (MDZ, i.m.). (B) Average seizure stage each minute following DFP (mixed measures ANOVA, n = 7–8). (C) Number of minutes in a CS prior to MDZ administration; (D) Average change in body weight after DFP intoxication. t-test or mixed measures ANOVA (n = 7–8).