Table 3. Receiver operating characteristic curves data for CRP, ferritin, D-dimer and copeptin as biomarkers of severity in COVID-19 Patients.
| Biomarker | Cut-off point | AUC | Sensitivity (%) | Specificity (%) | 95% CI | p-value |
|---|---|---|---|---|---|---|
| CRP | >3.55 mg/l | 0.824 | 83.33 | 73.33 | 0.713–0.935 | <0.0001† |
| Ferritin | >57.15 ng/ml | 0.816 | 80 | 70 | 0.705–0.926 | <0.0001† |
| D-dimer | >421 ng/ml | 0.728 | 73.33 | 50 | 0.600–0.855 | 0.002† |
| Copeptin | >18.50 Pmol/l | 0.969 | 93.33 | 100 | 0.926–1.013 | <0.0001† |
†
Significant at p < 0.05.
AUC: Area under the curve; CRP: C-reactive protein.