Table 5.
BMD associated serum metabolites.
| m/z | RT | VIP | βadj | P-value | FDR | |
|---|---|---|---|---|---|---|
| Alpha-D-Glucose | 179.05 | 192.7 | 2.83 | 0.13 | 0.003 | 0.92 |
| Hippuric acid | 178.05 | 192.7 | 2.10 | 0.10 | 0.017 | 0.92 |
| Glycolithocholic acid | 432.31 | 191.3 | 1.50 | 0.10 | 0.017 | 0.92 |
| LysoPC (18:0) | 524.37 | 40.6 | 2.14 | -0.10 | 0.019 | 0.92 |
| D-Ribose | 149.04 | 303.0 | 1.70 | 0.10 | 0.020 | 0.92 |
| 3-Phenylpropanoic acid | 149.06 | 83.5 | 1.95 | 0.10 | 0.022 | 0.92 |
| Palmitic acid | 315.25 | 41.2 | 1.94 | -0.10 | 0.022 | 0.92 |
| 1,7-Dimethylxanthine | 181.07 | 57.5 | 2.47 | 0.09 | 0.026 | 0.92 |
| Dodecanoic acid | 199.17 | 88.2 | 2.52 | -0.09 | 0.028 | 0.92 |
| Histidinyl glycine | 195.09 | 36.8 | 2.77 | 0.09 | 0.028 | 0.92 |
| Quinate | 191.05 | 326.0 | 2.57 | 0.09 | 0.039 | 0.92 |
| 3-Hydroxydodecanoic acid | 431.34 | 36.6 | 2.07 | -0.09 | 0.033 | 0.92 |
| DAG (18:0/20:4) | 627.53 | 189.3 | 1.90 | -0.09 | 0.042 | 0.92 |
| PC (18:0/18:1(9Z)) | 832.58 | 41.5 | 2.27 | -0.08 | 0.057 | 0.92 |
| Alpha-linolenic acid | 277.21 | 37.2 | 2.03 | -0.07 | 0.093 | 0.92 |
| Urea | 61.04 | 86.5 | 2.11 | -0.07 | 0.120 | 0.92 |
| 2-Methyl-3-hydroxybutyrate | 182.08 | 305.2 | 2.05 | 0.05 | 0.211 | 0.92 |
m/z denotes mass-to-charge ratio, RT indicates retention time. VIP refers to the variable importance in projection score provided by PLS. βadj and p-values correspond to the effects of metabolites individually tested in linear regression adjusted for age, BMI, exercise, years since menopause, FSH, and estradiol.