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. 2022 Jan 11;40(10):1081–1090. doi: 10.1200/JCO.21.01861

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FIG 2. — TNM staging of pediatric and adult thyroid cancers according to mutational status. (A and B) Tumor size, (C and D) lymph node metastasis, and (E and F) distant metastasis classification of pediatric DTC (N = 131; combined CSTP and miRInform samples) and adult DTCs (N = 496; TCGA) categorized by indeterminate, RAS-mut, BRAF-mut, and RET/NTRK fusion variants. CSTP, CHOP Solid Tumor Panel; DTC, differentiated thyroid cancer; M, distant metastasis status; N, lymph node; T, tumor status; TCGA, The Cancer Genome Atlas.