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. 2012 Apr 18;2012(4):CD009200. doi: 10.1002/14651858.CD009200.pub2

Nesheim 1983.

Methods Randomised.
Participants 115 women in labour at 4‐6 cm cervical dilatation.
Interventions PCB was administered with Kobac needle at the 3, 4.30, 7.30, 9 o'clock positions.
Group 1 (n = 43) ‐ 0.25% 20 mL bupivacaine.
Group 2 (n = 22) ‐ 0.25% 20 mL bupivacaine with adrenaline 1:400,000.
Group 3 (n = 28) ‐ 2% 20 mL chloroprocaine.
Group 4 (n = 22) ‐ 2% 20 mL chloroprocaine with adrenaline 1:400,000.
All blocks were given by either of 2 experienced obstetricians.
Outcomes Pain relief on 10 cm visual analogue scale ‐ patient was asked a few minutes after she received the block to indicate the degree of pain she had before and after receiving the block.
Duration of the block, time from PCB to fully dilatation, use of oxytocin, birthweight, Apgar score and method of delivery.
Notes No outcomes assessed in our review were reported in this study.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomisation was done by tossing a coin twice, e.g. the first toss determined which anaesthetic, the second toss whether adrenalin should be used.
Allocation concealment (selection bias) Unclear risk Not described.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not blinded.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Not blinded.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Complete data.
Selective reporting (reporting bias) High risk The authors reported Apgar score below 9 (not conventional 7) at 5 minutes, which is most likely underreporting of negative effect of intervention.
Other bias Low risk No other bias identified.