(A) Positive end-expiratory pressure (PEEP) as a function of time as measured on the benchtop test setup for the O2U ventilator (left) PEEP at 5 cmH2O and (right) 15 cmH2O set via an external diaphragm valve on the O2U ventilator, x-axis is time. (B) Inspiration time is the duration of time that the gas is delivered to the patient. This is important to be able to vary to manage different lung care strategies and ventilation parameters. Shown here is the difference between 1.0 s and 1.6 s on the dynamic effects on the flow and PEEP pressure signals, x-axis is time. (C) Tidal volume, or the volume delivered to the patient is a critical variable in patient care to ensure adequate oxygenation while not over pressurizing the lungs. The O2U ventilator is capable of providing greater than the FDA-required range to manage the majority of COVID-19 patients. This range is shown in 50 mL increments from 300 mL to 500 mL, x-axis is time. (D) Breath rate (and inspiratory time) controls the minute volume of gas (L/min) supplied to the patient. Control of the breath rate is essential for patient care as this varies based on patient age and underlying conditions and can often change during ventilation. These graphs show 10 (top), 15 (mid), and 20 (bottom) breaths per minute as set by the UI of the O2U ventilator for a flow rate of 50 L/min, x-axis is time.