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. 2022 Mar 30;17(3):e0266173. doi: 10.1371/journal.pone.0266173

Table 2. Ventilator parameters used for the benchtop testing as required for FDA EUA ventilator requirements as well as the animal ventilation test showing the phases of simulated ventilation treatment.

Parameters for Benchtop and Animal Testing
Test/Phase PEEP (cmH2O) Breath Rate (breaths/min) Tidal Volume (mL) iTime (s)
Benchtop Tests
    PEEP Test 5 | 15 10 500 1
    Breath Rate Test 5 10 | 15 | 20 500 1
    Tidal Volume Test 5 10 300 | 350 | 400 | 450 | 500 1
    iTime Test 5 10 500 1.0 | 1.6
Animal Protocol Phases
    Baseline 5 10 650 1.2
    Hyperventilation 5 10 850 1.6
    Hypoventilation 5 10 440 0.8
    Baseline/Recovery 5 10 650 1.2