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. 2021 Aug 11;145(1):208–223. doi: 10.1093/brain/awab299

Figure 4.

Figure 4

MRI studies from Patient 1. (A) At age 37 years: T2-FLAIR subcortical hyperintense non-enhancing foci localized to the frontal, temporo-occipital and visual cortices bilaterally with prominent involvement of calcarine cortex (yellow arrows). (B) At age 38 years: severe and diffuse cortical and subcortical atrophy (red arrows).