Table 2.
Interactions of NDUFS4 and NDUFA12 with other CI subununits
| Subunit | Modulea | Interacting withb | |||
|---|---|---|---|---|---|
| NDUFS4 | NDUFA12 | ||||
| Ovine | Bovine | Ovine | Bovine | ||
| NDUFV1/51-kDa | N | X | X | — | — |
| NDUFV2/24-kDa | N | X | — | — | — |
| NDUFV3-10/10-kDa | N | X | X | — | — |
| NDUFS1/75-kDa | N | X | X | X | X |
| NDUFS6/13-kDa | N | — | — | X | X |
| NDUFA12/B17.2 | N | X | X | NA | NA |
| NDUFS4/18-kDa | N/Q? | NA | NA | X | X |
| NDUFS2/49-kDa | Q | — | X | — | — |
| NDUFS3/30-kDa | Q | X | X | — | — |
| NDUFS7/PSST | Q | — | — | X | X |
| NDUFS8/TYKY | Q | X | X | X | X |
| NDUFA6/B14 | Q | X | X | — | — |
| NDUFA7/B14.5a | Q | — | — | X | X |
| NDUFA9/39-kDa | Q | X | X | — | — |
| MT-ND1/ND1 | Pp | — | — | X | X |
| NDUFA1/MWFE | Pp | — | — | — | X |
For each subunit the human (according to HGNC: www.genenames.org) and bovine names (kDa) are given. Core subunit are highlighted in bold, mtDNA-encoded subunits are highlighted in italics. NA = not appropriate.
a
Functional modules: N (NADH binding and oxidation), Q (electron transfer to ubiquinone), P module (consisting of Pp and Pd submodules, proton pumping).