Figure 3-. Principal component analysis (PCA) of species sequence data and partial Least Squares Discriminant Analysis (PLS-DA) analysis of the high-dimensional data. (A) Principal component analysis (PCA) showed that the vaginal microbiota identified three major clusters L. crispatus (CST I), L. iners (CST II), and depleted of L. spp. with high diversity (CST III). (B) Partial least square discriminant score plot of vaginal microbiota between the normal, HPV, LSIL, HSIL and cancer groups.
