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. 2022 Feb 28;14(2):e22688. doi: 10.7759/cureus.22688

Table 3. Associations between HbA1c levels and PHQ-9 scores.

Note: Adjusted model included sex, race/ethnicity, poverty, body mass index, and sedentary lifestyle, all of which are shown in the table.

PHQ-9: Patient Health Questionnaire; HbA1c: hemoglobin A1c.

Patient characteristics   Unadjusted Adjusted
    OR (95% CI) P-value OR (95% CI) P-value
HbA1c ≤7% 1.47 (1.04, 2.09) 0.033 1.23 (0.85, 1.78) 0.256
  >7% Ref   Ref  
Sex Male Ref   Ref  
  Female 1.72 (0.73, 4.03) 0.195 1.60 (0.71, 3.60) 0.239
Race/ethnicity White non-Hispanic Ref   Ref  
  Black non-Hispanic  0.81 (0.32, 2.05) 0.629 0.70 (0.30, 1.65) 0.388
  Hispanic 0.48 (0.22, 1.08) 0.073 0.41 (0.16, 1.03) 0.057
  Other/mixed 0.83 (0.30, 2.27) 0.692 1.11 (0.36, 3.45) 0.840
Family income to poverty ≤1.30  2.41 (0.81, 7.21) 0.11 2.93 (1.01, 8.50) 0.048
  1.3-3.50 1.63 (0.51, 5.15) 0.88 2.12 (0.69, 6.50) 0.175
  >3.50 Ref   Ref  
Body mass index <25 Ref   Ref  
  25.0-30 1.58 (0.35, 7.12) 0.53 1.57 (0.33, 7.32) 0.545
  >30 2.78 (0.67, 11.51) 0.14 2.01 (0.52, 7.69) 0.286
Sedentary lifestyle <5 hours/day Ref   Ref  
  5-10 hours/day 2.51 (1.59, 3.94) 0.001 2.70 (1.58, 4.61) 0.001
  >10 hours/day 3.36 (1.17, 9.64) 0.027 5.16 (1.73, 15.40) 0.006