Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 14;10:817028. doi: 10.3389/fcell.2022.817028

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhang, Xia, Yao, Jiang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The silence of circSSU72 inhibited PTC cell proliferation, migration, and invasion by targeting miR-451a. (A) The expression of miR-451a in TPC-1 and IHH-4 cells with the transfection of miR-451a inhibitor (n = 3). (B) Colony formation assay of the cell proliferation ability in TPC-1 cell transfected with si-circSSU72 and miR-451a inhibitor (n = 3). (C) CCK8 assay to assess the influence of circSSU72 and miR-451a on TPC-1 cell (n = 3). (D) EdU assay of the cell proliferation ability in TPC-1 cell transfected with si-circSSU72 and miR-451a inhibitor (scale bar = 100 um, n = 4). (E) Scratch wound healing assays in transfected TPC-1 cell (scale bar = 200 um, n = 3). (F) Transwell invasion and migration assay in transfected TPC-1 cell (scale bar = 100 um, n = 3). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.