Table 1.

Proteins present in heart mitochondria post sericin-treated hypercholesterolemic rats.

Spot No.	Intensity		ANOVA	Gene name	Protein name	Score	MW	pI	%Sequence coverage	Mitochondria related function
	Treatment	Non-treatment
1	0.0398	ND	0.0046	HSPA9	Stress-70 protein	43	73970	5.87	7	Iron-sulfur cluster biogenesis (Alfadhel et al. 2017; Lill and Freibert 2020), Cardioprotection (antiapoptosis) (Gao et al. 2015)
2	0.1927	ND	0.0045	Hsdl2	Hydroxysteroid dehydrogenase-like protein 2	286	58649	5.85	10	Fatty acid oxidation (Gronemeyer et al. 2013)
3	0.0833	ND	0.0358	Hsdl2	Hydroxysteroid dehydrogenase-like protein 2	532	58649	5.85	17
4	0.1104	ND	0.0359	Sdha	Succinate dehydrogenase [ubiquinone] flavoprotein subunit	133	72596	6.75	3	Electron transport chain (Renkema et al. 2015), Mutation is cause of cardiomyopathy (Levitas et al. 2010)
5	0.1433	ND	0.0234	Acss1	Acetyl-coenzyme A synthetase 2-like	101	75317	6.51	6	Pyruvate metabolism, Oxidation under ketogenic condition (Fujino et al. 2001)
6	0.0230	ND	0.0098	Dld	Dihydrolipoyl dehydrogenase	81	54574	7.96	9	Pyruvate metabolism (Igamberdiev et al. 2004), Cardioprotection (antioxidative stress) (Igamberdiev et al. 2004)
7	0.0334	ND	0.0064	Fh	Fumarate hydratase	528	54714	9.06	15	Krebs cycle (Ajalla Aleixo et al. 2019)
8	0.1222	ND	0.0023	Idh2	Isocitrate dehydrogenase [NADP]	2797	51330	8.88	30	Pyruvate metabolism (Smolkova and Jezek 2012), Cardioprotection (antioxidative stress) (Benderdour et al. 2004)

MW: molecular weight, pI: isoelectric point.