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. 2022 Mar 29;37(1):895–911. doi: 10.1080/14756366.2022.2051022

Table 3.

IC50 values of PI3Kγ, PI3Kδ, and AKT Inhibition of compounds 4d and 7f.

    IC50 (uM)a**
Compounds PI3Kγ PI3Kδ AKT
4d 35.10 ± 1.82 23.90 ± 1.20 7.67 ± 0.40
7f 6.99 ± 0.36 4.01 ± 0.55 3.36 ± 0.17
LY294002 15.7 ± 0.81 13.4 ± 0.67
LY2780301 4.62 ± 0.24

aIC50 values are the mean ± SD of three separate experiments.

**p < .01.