FIGURE 4.

(A). Patients who improved within 7 days and those who improved after 7 days following treatment were categorized into two separate groups. The Mann–Whitney U test was used to analyze the difference in the total IgE concentration between the two groups. Spearman's correlation analysis was used to analyze the correlation between the total IgE concentration measured at the first visit and the number of days needed for improvement. (B) After the follow‐up, the subjects were divided into a recurrence group (palindromia) and a non‐recurrence group (recovery). The Mann–Whitney U test was used to analyze the difference between the total IgE concentrations of both groups. Typical findings for a 37‐year‐old male SAC patient with (C) lower palpebral conjunctival and bulbar conjunctival reactions at the first visit; moderate hyperemia and edema are present. The concentration of total IgE in the tears was 7.94 IU/ml. (D) Lower palpebral conjunctival and bulbar conjunctival reaction at the first follow‐up visit; mild hyperemia and edema are present. The total IgE concentration was 2.10 IU/ml. (E) Lower palpebral conjunctival and bulbar conjunctival reactions at the second follow‐up visit. The total IgE concentration was 0.52 IU/ml