TABLE 2.

Characteristics of cryopreservation for childhood, adolescent, and young adult patients with breast cancer and hematologic malignancy

	Institutions, n		Patients, n		Number of patients per institution, median (range)		Patient age at cryopreservation, years, mean ± SD (range)
	Pre	Post	Pre	Post	Pre	Post	Pre	Post
Breast cancer	72	116	760	1535	4 (1–127)	6 (1–139)	35.5 ± 3.52 (20–48)	35.2 ± 2.56 (17–50)
Hematologic malignancy	50	73	216	393	2 (1–66)	3 (1–37)	27.0 ± 5.86 (5–42)	27.0 ± 5.17 (11–45)

Pre, 2011–2015, i.e., before publication of the Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 for Fertility Preservation in Childhood, Adolescent, and Young Adult Cancer Patients ⁸ , ⁹ ; post, 2016–2019, i.e., from shortly before to after publication of the guidelines.